Mafb^m1Gsb
Chemically induced Allele Detail

Summary

• Symbol: Mafb^m1Gsb
• Name: MAF bZIP transcription factor B; mutation 1, Gregory S Barsh
• MGI ID: MGI:2157803
• Synonyms: kreisler^enu, kr^ENU, MafB^ENU
• Gene: Mafb Location: Chr2:160205623-160208985 bp, - strand Genetic Position: Chr2, 80.92 cM
• Alliance: Mafb^m1Gsb page

Mutation origin

• Strain of Origin: (BALB/cJ x SJL/J)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: An A-to-G transition at nucleotide 743 resulted in an asparagine to serine substitution at amino acid 248. The mutation is in the putative DNA-binding domain and is conserved among other gene family members. (J:22020)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:

27 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mafb Mutation: 20 strains or lines available

References

• Original: J:22020 Cordes SP, et al., The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell. 1994 Dec 16;79(6):1025-34
• All: 5 reference(s)