About   Help   FAQ
Scc6BALB/cHeA
QTL Variant Detail
Summary
QTL variant: Scc6BALB/cHeA
Name: colon tumor susceptibility 6; BALB/cHeA
MGI ID: MGI:2157957
QTL: Scc6  Location: Chr11:6880277-89019734 bp  Genetic Position: Chr11, cM position of peak correlated region/allele: 7.3 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  BALB/cHeA
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    This allele confers resistance to colon tumors compared to STS/A.
Inheritance:    Not Specified
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:57235

Susceptibility to colon cancer was analyzed in CcS (Background = BALB/cHeA Donor = STS/A )recombinant congenic strains CcS-3, CcS-5 and CcS-11. Susceptibility locus Scc6 was associated with mouse Chromosome 11 marker D11Mit2 within a range from marker D11Mit71 to marker D11Mit162.

References
Original:  J:57235 van Wezel T, et al., Four new colon cancer susceptibility loci, Scc6 to Scc9 in the mouse. Cancer Res. 1999 Sep 1;59(17):4216-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory