Vispl^C57BL/6By
QTL Variant Detail

Summary

• QTL variant: Vispl^C57BL/6By
• Name: visual placing; C57BL/6By
• MGI ID: MGI:2157988
• QTL: Vispl Location: Chr11:118022590-118022724 bp Genetic Position: Chr11, cM position of peak correlated region/allele: 82.96 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6By

Variant description

• Allele Type: QTL
• Inheritance: Recessive

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:53794

Nineteen measures of sensorial, motor and body weight were subject to analysis in 389 female and male mice derived from reciprocal F1 and F2 mating of strains C57BL6/By and NZB/BlNJ . These traits were mapped via QTL analysis. In total 36 traits were mapped to chromosomes of which a number reached a threshold LOD score of 3.13 and were thus concidered significant. One such QTL, visual placing (vispl) mapped with mouse Chromosome 11 marker D11Mit48 with a LOD score of 4.05. NZB/BlNJ-derived alleles confer later appearance of visual placing behavior compared to C57BL/6By. This was measured the day after eyelid opening by suspending pups by the tail and lowering them towards a pencil without the vibrissae touching it. The pup was observed whether or notit extended the paw to grasp the pencil.

References

• Original: J:53794 Le Roy I, et al., Preweanling sensorial and motor development in laboratory mice: quantitative trait loci mapping. Dev Psychobiol. 1999 Mar;34(2):139-58
• All: 1 reference(s)