Alcp19^A/J
QTL Variant Detail

Summary

• QTL variant: Alcp19^A/J
• Name: alcohol preference locus 19, female specific; A/J
• MGI ID: MGI:2158135
• QTL: Alcp19 Location: unknown Genetic Position: Chr11, Syntenic

Variant origin

• Strain of Specimen: A/J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers decreased alcohol consumption in female animals compared to C57BL/6J. (J:52467)
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:52467

Alcohol consumption and preference in mice were analyzed as a QTL in Recombinant Inbreds(RI) AXB and BXA and progenitor inbreds C57BL/6J and A/J. In males QTLs were found on mouse Chromosomes 2, 5, 7, 10, 11 and 16. and in females QTLs were found on Chromosomes 2, 4, 5, 7, 11, 16, and 19. A QTL for alcohol preference in male AXB/BXA mice was associated with marker D11Mit35 and is designated as Alcp17. An additional male QTL was associated with D11Mit61 with a LOD score of 2.0 and is designated as Alcp18. In addition A QTL for alcohol preference in female AXB/BXA mice was also associated with marker D11Mit35 with a LOD score of 2.37 and is designated as Alcp19. An additional female QTL was associated with D11Mit61 and is designated as Alcp20.

References

• Original: J:52467 Gill K, et al., Alcohol preference in AXB/BXA recombinant inbred mice: gender differences and gender-specific quantitative trait loci. Mamm Genome. 1998 Dec;9(12):929-35
• All: 1 reference(s)