Cd2tm1Litt
Targeted Allele Detail
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| Symbol: |
Cd2tm1Litt |
| Name: |
CD2 antigen; targeted mutation 1, Dan R Littman |
| MGI ID: |
MGI:2158301 |
| Synonyms: |
CD2-, Cd2tm1Drl |
| Gene: |
Cd2 Location: Chr3:101183224-101195255 bp, - strand Genetic Position: Chr3, 44.17 cM
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| Alliance: |
Cd2tm1Litt page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:3149
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| Parent Cell Line: |
D3 (ES Cell)
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| Strain of Origin: |
129S2/SvPas
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Insertion
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Mutation details: A neomycin selection cassette was inserted into exon 2, into sequences encoding the amino terminal V-like domain. Northern blot analysis demonstrated that no stable transcript was produced from this allele. Immunocytochemistry analysis demonstrated that no functional protein was present on the surface of lymphocytes.
(J:3149)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Cd2 Mutation: |
18 strains or lines available
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| Original: |
J:3149 Killeen N, et al., Development and function of T cells in mice with a disrupted CD2 gene. EMBO J. 1992 Dec;11(12):4329-36 |
| All: |
10 reference(s) |
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Analysis Tools
