Bcl2l1^tm1Dlo
Targeted Allele Detail

Summary

• Symbol: Bcl2l1^tm1Dlo
• Name: BCL2-like 1; targeted mutation 1, Dennis Y Loh
• MGI ID: MGI:2158303
• Synonyms: bcl-x-
• Gene: Bcl2l1 Location: Chr2:152622588-152673648 bp, - strand Genetic Position: Chr2, 75.41 cM, cytoband H1
• Alliance: Bcl2l1^tm1Dlo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:23793
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic fragment containing the initiation codon was replaced with a neomycin or hygromycin selection cassette. (J:23793)

Expression

In Mice Carrying this Mutation:

61 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl2l1 Mutation: 104 strains or lines available

References

• Original: J:23793 Motoyama N, et al., Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science. 1995 Mar 10;267(5203):1506-10
• All: 20 reference(s)