Coq7^tm1Tsh
Targeted Allele Detail

Summary

• Symbol: Coq7^tm1Tsh
• Name: demethyl-Q 7; targeted mutation 1, Takuji Shirsawa
• MGI ID: MGI:2158322
• Synonyms: coq7-
• Gene: Coq7 Location: Chr7:118108881-118132529 bp, - strand Genetic Position: Chr7, 63.44 cM
• Alliance: Coq7^tm1Tsh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:73111
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exon 2. Western blot analysis did not detect immunoreactivity in homozygous mutant E9.5 embryo extracts. (J:73111)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Coq7 Mutation: 29 strains or lines available

References

• Original: J:73111 Nakai D, et al., Mouse Homologue of coq7/clk-1, Longevity Gene in Caenorhabditis elegans, Is Essential for Coenzyme Q Synthesis, Maintenance of Mitochondrial Integrity, and Neurogenesis. Biochem Biophys Res Commun. 2001 Nov 30;289(2):463-71
• All: 4 reference(s)