Bmpr1a^tm2Bhr
Targeted Allele Detail

Summary

• Symbol: Bmpr1a^tm2Bhr
• Name: bone morphogenetic protein receptor, type 1A; targeted mutation 1, Richard R Behringer
• MGI ID: MGI:2158343
• Synonyms: Bmpr1a^cl, Bmpr1a^fn, Bmpr1a^tm1Cren, floxP-neo
• Gene: Bmpr1a Location: Chr14:34133018-34225335 bp, - strand Genetic Position: Chr14, 20.81 cM
• Alliance: Bmpr1a^tm2Bhr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75074
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Homologous recombination introduced a loxP-flanked neomycin resistance cassette into intron 2, and a single loxP site into intron 1. (J:75074)

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmpr1a Mutation: 90 strains or lines available

References

• Original: J:75074 Mishina Y, et al., Generation of Bmpr/Alk3 conditional knockout mice. Genesis. 2002 Feb;32(2):69-72
• All: 10 reference(s)