Mas1^tm1Bdr
Targeted Allele Detail

Summary

• Symbol: Mas1^tm1Bdr
• Name: MAS1 oncogene; targeted mutation 1, Michael Bader
• MGI ID: MGI:2158808
• Synonyms: Mas -
• Gene: Mas1 Location: Chr17:13059966-13087030 bp, - strand Genetic Position: Chr17, 8.69 cM
• Alliance: Mas1^tm1Bdr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:47445
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin selection cassette replaced sequences encoding the amino-terminal 253 amino acids of the protein. RNAse protection assays on RNA derived from brain and testis of homozygous mice confirmed that no transcript containing coding sequences is produced from this allele. (J:47445)

Expression

In Mice Carrying this Mutation:	57 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mas1 Mutation: 24 strains or lines available

References

• Original: J:47445 Walther T, et al., Sustained long term potentiation and anxiety in mice lacking the Mas protooncogene. J Biol Chem. 1998 May 8;273(19):11867-73
• All: 38 reference(s)