Oprm1^tm1Lyu
Targeted Allele Detail

Summary

• Symbol: Oprm1^tm1Lyu
• Name: opioid receptor, mu 1; targeted mutation 1, Lei Yu
• MGI ID: MGI:2159002
• Gene: Oprm1 Location: Chr10:6708593-6988209 bp, + strand Genetic Position: Chr10, 1.85 cM, cytoband A2
• Alliance: Oprm1^tm1Lyu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:39864
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin selection cassette replaced a genomic fragment containing the first coding exon. (J:39864)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Oprm1 Mutation: 54 strains or lines available

References

• Original: J:39864 Tian M, et al., Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice. J Exp Med. 1997 Apr 21;185(8):1517-22
• All: 1 reference(s)