Neurog2^tm1Fgu
Targeted Allele Detail

Summary

• Symbol: Neurog2^tm1Fgu
• Name: neurogenin 2; targeted mutation 1, Francois Guillemot
• MGI ID: MGI:2159009
• Synonyms: Math4a-, ngn2-, Ngn2^delta
• Gene: Neurog2 Location: Chr3:127426784-127429280 bp, + strand Genetic Position: Chr3, 56.54 cM, cytoband H1
• Alliance: Neurog2^tm1Fgu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:46667
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin selection cassette replaced a genomic fragment containing exon 2, which includes the entire coding region of the gene.

Expression

In Mice Carrying this Mutation:	151 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Neurog2 Mutation: 18 strains or lines available

References

• Original: J:46667 Fode C, et al., The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Neuron. 1998 Mar;20(3):483-94
• All: 14 reference(s)