Anxa6^tm1Moss
Targeted Allele Detail

Summary

• Symbol: Anxa6^tm1Moss
• Name: annexin A6; targeted mutation 1, Stephen E Moss
• MGI ID: MGI:2159012
• Synonyms: annexin 6^-, annexin VI-
• Gene: Anxa6 Location: Chr11:54869934-54924271 bp, - strand Genetic Position: Chr11, 32.13 cM
• Alliance: Anxa6^tm1Moss page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:58609
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin selection cassette was inserted into exon 3. Western blot analysis on samples derived from spleen, heart and liver of homozygous mice demonstrated that no detectable protein was produced from this allele. (J:58609)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Anxa6 Mutation: 42 strains or lines available

References

• Original: J:58609 Hawkins TE, et al., Immunological development and cardiovascular function are normal in annexin VI null mutant mice. Mol Cell Biol. 1999 Dec;19(12):8028-32
• All: 9 reference(s)