Tg(HLA-B27)30-4Trg
Transgene Detail

Summary

• Symbol: Tg(HLA-B27)30-4Trg
• Name: transgene insertion 30-4, Joel D Taurog
• MGI ID: MGI:2159095
• Synonyms: HLA-B27, Tg(HLA*B27)30-4Trg, Tg(HLA-B27)30-4Trg, Tg(HLA-B)30-4Trg
• Transgene: Tg(HLA-B27)30-4Trg Location: unknown
• Alliance: Tg(HLA-B27)30-4Trg page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A transgene containing the human HLA-B allele, HLA-B27, was shown to be expressed in spleen cells of mice carrying the transgene. (J:74663)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:74663 Taurog JD, et al., HLA-B27 in inbred and non-inbred transgenic mice. Cell surface expression and recognition as an alloantigen in the absence of human beta 2-microglobulin. J Immunol. 1988 Dec 1;141(11):4020-3
• All: 2 reference(s)