About   Help   FAQ
Tg(HLA-B)22Hpl
Transgene Detail
Summary
Symbol: Tg(HLA-B)22Hpl
Name: transgene insertion 22, Hidde Ploegh
MGI ID: MGI:2159100
Synonyms: HLA-B27, HLA-B27.2
Transgene: Tg(HLA-B)22Hpl  Location: unknown  
Alliance: Tg(HLA-B)22Hpl page
Transgene
origin
Strain of Origin:  (CBA x C57BL/LiA)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA transgene containing the human HLA-B allele, HLA-B27, was shown to be expressed in spleen cells of mice carrying the transgene. (J:74416)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:74416 Krimpenfort P, et al., Crosses of two independently derived transgenic mice demonstrate functional complementation of the genes encoding heavy (HLA-B27) and light (beta 2-microglobulin) chains of HLA class I antigens. EMBO J. 1987 Jun;6(6):1673-6
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/22/2024
MGI 6.24
The Jackson Laboratory