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Tg(HLA-B)22Hpl
Transgene Detail
Summary
Symbol: Tg(HLA-B)22Hpl
Name: transgene insertion 22, Hidde Ploegh
MGI ID: MGI:2159100
Synonyms: HLA-B27, HLA-B27.2
Transgene: Tg(HLA-B)22Hpl  Location: unknown  
Alliance: Tg(HLA-B)22Hpl page
Transgene
origin
Strain of Origin:  (CBA x C57BL/LiA)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA transgene containing the human HLA-B allele, HLA-B27, was shown to be expressed in spleen cells of mice carrying the transgene. (J:74416)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:74416 Krimpenfort P, et al., Crosses of two independently derived transgenic mice demonstrate functional complementation of the genes encoding heavy (HLA-B27) and light (beta 2-microglobulin) chains of HLA class I antigens. EMBO J. 1987 Jun;6(6):1673-6
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory