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Tg(HLA-B27)1Trg
Transgene Detail
Summary
Symbol: Tg(HLA-B27)1Trg
Name: transgene insertion 1, Joel D Taurog
MGI ID: MGI:2159102
Synonyms: line 56-3
Transgene: Tg(HLA-B27)1Trg  Location: unknown  
Alliance: Tg(HLA-B27)1Trg page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL/J)F2
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA transgene containing the human HLA-B allele, HLA-B27, was shown to be expressed in spleen cells of mice carrying the transgene. The HLA-B2705 and human B2M ( Tg(B2M)1Trg) constructs were co-injected and co-integrated. The line is designated 56-3. (J:74451)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:74451 Taurog JD, et al., HLA-B27 Transgenic Mice as Potential Models of Human Disease, in Transgenic Mice and Mutants in MHC Research. 1990:268-75.
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory