Shc1^tm1Pgp
Targeted Allele Detail

Summary

• Symbol: Shc1^tm1Pgp
• Name: src homology 2 domain-containing transforming protein C1; targeted mutation 1, Pier G Pelicci
• MGI ID: MGI:2159438
• Synonyms: p66^shc-, p66^shc, p66Shc-
• Gene: Shc1 Location: Chr3:89325858-89337336 bp, + strand Genetic Position: Chr3, 39.11 cM
• Alliance: Shc1^tm1Pgp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:58535
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Mutation details: This allele is a targeted mutation of the exon that encodes the CH2 region. Further details are referenced as "in preparation". (J:58535)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shc1 Mutation: 66 strains or lines available

References

• Original: J:58535 Migliaccio E, et al., The p66shc adaptor protein controls oxidative stress response and life span in mammals [see comments]. Nature. 1999 Nov 18;402(6759):309-13
• All: 57 reference(s)