Arfrp1^tm1Asch
Targeted Allele Detail

Summary

• Symbol: Arfrp1^tm1Asch
• Name: ARF related protein 1; targeted mutation 1, A Schurmann
• MGI ID: MGI:2159671
• Gene: Arfrp1 Location: Chr2:180999483-181007197 bp, - strand Genetic Position: Chr2, 103.63 cM
• Alliance: Arfrp1^tm1Asch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:74645
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3, containing the start codon, the PM1-PM3 motifs, and the G1 motif, were replaced with a neomycin resistance cassette. (J:74645)

Expression

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arfrp1 Mutation: 19 strains or lines available

References

• Original: J:74645 Mueller AG, et al., Embryonic Lethality Caused by Apoptosis during Gastrulation in Mice Lacking the Gene of the ADP-Ribosylation Factor-Related Protein 1. Mol Cell Biol. 2002 Mar;22(5):1488-94
• All: 3 reference(s)