Mia^tm1Rbu
Targeted Allele Detail

Summary

• Symbol: Mia^tm1Rbu
• Name: MIA SH3 domain containing; targeted mutation1, Reinhard Buettner
• MGI ID: MGI:2159701
• Synonyms: MIA^-, MIA/CD-RAP^-
• Gene: Mia Location: Chr7:26879166-26880574 bp, - strand Genetic Position: Chr7, 15.84 cM
• Alliance: Mia^tm1Rbu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:74659
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The neomycin cassette is inserted between exons 2 and 4. The allele encodes a truncated 57 amino acid protein.

Expression

In Mice Carrying this Mutation:

41 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mia Mutation: 15 strains or lines available

References

• Original: J:74659 Moser M, et al., Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice. Mol Cell Biol. 2002 Mar;22(5):1438-45
• All: 3 reference(s)