Tg(Mx1-cre)1Cgn
Transgene Detail

Summary

• Symbol: Tg(Mx1-cre)1Cgn
• Name: transgene insertion 1, University of Cologne
• MGI ID: MGI:2176073
• Synonyms: Mx1-Cre, Mx1cre, Mx-Cre, MxCre, Mx-Cre 31, MxCre^Tg, Tg(Mx1-cre)^hemi
• Transgene: Tg(Mx1-cre)1Cgn Location: unknown Genetic Position: Chr10, Syntenic
• Alliance: Tg(Mx1-cre)1Cgn page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F2

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: interferon or polyinosinic-polycytidylic acid
• Mutation: Insertion
• Tg(Mx1-cre)1Cgn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Mx1

• Mutation details: This transgene expresses Cre recombinase under the control of an inducible Mx1 promoter, which is silent in healthy mice, and active in the liver and in lymphocytes after induction with IFN or pI-pC. The construct also contains a 2.1 kb fragment from the human growth hormone gene. (J:67927)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mx1 (species not specified) Summary of all recombinase alleles driven by Mx1. Comparative matrix view of recombinase activities

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Mx1-cre)1Cgn

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 7 strains available Cell Lines: 0 lines available

References

• Original: J:67927 Kuhn R, et al., Inducible gene targeting in mice. Science. 1995 Sep 8;269(5229):1427-9
• All: 1337 reference(s)