Tg(GZMB-cre)1Jcb
Transgene Detail

Summary

• Symbol: Tg(GZMB-cre)1Jcb
• Name: transgene insertion 1, Joshy Jacob
• MGI ID: MGI:2176191
• Synonyms: granzyme-B-Cre
• Transgene: Tg(GZMB-cre)1Jcb Location: unknown
• Alliance: Tg(GZMB-cre)1Jcb page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(GZMB-cre)1Jcb expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  GZMB (3002)

  Gzmb	(MGI:109267)
  Gzmc	(MGI:109256)
  Gzmd	(MGI:109255)
  Gzme	(MGI:109265)
  Gzmf	(MGI:109254)
  Gzmg	(MGI:109253)
  Gzmn	(MGI:2675494)

• Mutation details: This transgene expresses Cre recombinase under the control of a human granzyme B (GZMB) promoter, active specifically in activated T cells. (J:67937)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	GZMB (human) Summary of all recombinase alleles driven by GZMB. Comparative matrix view of recombinase activities Alliance human GZMB gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:67937 Jacob J, et al., Modelling T-cell memory by genetic marking of memory T cells in vivo. Nature. 1999 Jun 10;399(6736):593-7
• All: 44 reference(s)