Tg(Pax3-cre)1Joe
Transgene Detail

Summary

• Symbol: Tg(Pax3-cre)1Joe
• Name: transgene insertion 1, Jonathan A Epstein
• MGI ID: MGI:2176205
• Synonyms: P3Pro-Cre, Pax3Cre^T, Pax3-Cre^tg, Pax3-Pro-Cre
• Transgene: Tg(Pax3-cre)1Joe Location: unknown
• Alliance: Tg(Pax3-cre)1Joe page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pax3-cre)1Joe expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pax3 (MGI:97487)

• Mutation details: This transgene expresses Cre recombinase under the control of the mouse Pax3 promoter. This promoter is active in embryonic neural crest cells. Cre recombinase activity is also detected in early metanephric mesenchymal lineages but not in the nephric duct or ureteric bud tissues. (J:69319, J:107078)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pax3 (mouse) Summary of all recombinase alleles driven by Pax3. Comparative matrix view of recombinase activities Alliance mouse Pax3 gene page

Disease models

Expression

In Mice Carrying this Mutation:

49 assay results 2 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Pax3-cre)1Joe

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:69319 Li J, et al., Neural crest expression of Cre recombinase directed by the proximal Pax3 promoter in transgenic mice. Genesis. 2000 Feb;26(2):162-4
• All: 48 reference(s)