Tg(Hoxa1-cre)1Tlu
Transgene Detail

Summary

• Symbol: Tg(Hoxa1-cre)1Tlu
• Name: transgene insertion 1, Thomas Lufkin
• MGI ID: MGI:2176212
• Synonyms: EIII-Cre
• Transgene: Tg(Hoxa1-cre)1Tlu Location: unknown
• Alliance: Tg(Hoxa1-cre)1Tlu page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2J)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Hoxa1-cre)1Tlu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hoxa1 (MGI:96170)

• Mutation details: This transgene expresses a bicistronic mRNA containing Cre recombinase sequences and an IRES-human placental alkaline phosphatase under the control of the mouse Hoxa1 enhancer III and a basal TATA box promoter. This enhancer/promoter is active in embryonic floorplate, notochord and gut epithelium beginning at E8.5 through E14.5. (J:67902)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hoxa1 (mouse) Summary of all recombinase alleles driven by Hoxa1. Comparative matrix view of recombinase activities Alliance mouse Hoxa1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:67902 Li X, et al., Cre recombinase expression in the floorplate, notochord and gut epithelium in transgenic embryos driven by the Hoxa-1 enhancer III. Genesis. 2000 Feb;26(2):121-2
• All: 5 reference(s)