Foxq1^sa-e1
Chemically induced Allele Detail

Summary

• Symbol: Foxq1^sa-e1
• Name: forkhead box Q1; satin, ENU 1
• MGI ID: MGI:2176727
• Synonyms: Foxq1^ENU, satin
• Gene: Foxq1 Location: Chr13:31742153-31744959 bp, + strand Genetic Position: Chr13, 13.46 cM
• Alliance: Foxq1^sa-e1 page

Mutation origin

• Strain of Origin: (101/Rl x C3H/Rl)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation in this allele was identified as a T to G transversion that leads to a substitution of isoleucine to serine at amino acid position 128, located in the WH DNA-binding domain. (J:75422)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxq1 Mutation: 29 strains or lines available

References

• Original: J:75422 Hong HK, et al., The winged helix/forkhead transcription factor Foxq1 regulates differentiation of hair in satin mice. Genesis. 2001 Apr;29(4):163-71
• All: 3 reference(s)