Crygc^Chl3
Chemically induced Allele Detail

Summary

• Symbol: Crygc^Chl3
• Name: crystallin, gamma C; chlorambucil, exon 3
• MGI ID: MGI:2176919
• Gene: Crygc Location: Chr1:65110684-65112691 bp, - strand Genetic Position: Chr1, 32.81 cM
• Alliance: Crygc^Chl3 page

Mutation origin

• Strain of Origin: (102/El x C3H/El)

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Intragenic deletion
• Mutation details: A 6 bp deletion in exon 3 is causative for the cataract phenotype in this mouse. The deletion leads to the loss of two amino acids, Gly and Arg, in the fourth Greek-key motif. (J:73804)
• Inheritance: Dominant

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crygc Mutation: 13 strains or lines available

References

• Original: J:73804 Graw J, et al., A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse. Invest Ophthalmol Vis Sci. 2002 Jan;43(1):236-40
• All: 2 reference(s)