Cebpa^tm1.1Gonz
Targeted Allele Detail

Summary

• Symbol: Cebpa^tm1.1Gonz
• Name: CCAAT/enhancer binding protein alpha; targeted mutation 1.1, Frank Gonzalez
• MGI ID: MGI:2177135
• Synonyms: c/ebpalpha-
• Gene: Cebpa Location: Chr7:34818718-34821353 bp, + strand Genetic Position: Chr7, 21.02 cM
• Alliance: Cebpa^tm1.1Gonz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:42995
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Coding sequences of the gene were deleted in the germline by crossing mice carrying Cebpa^tm1Gonz to mice carrying Tg(EIIa-Cre)1Lmgd. (J:42995)

Expression

In Mice Carrying this Mutation:

16 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cebpa Mutation: 19 strains or lines available

References

• Original: J:42995 Lee YH, et al., Disruption of the c/ebp alpha gene in adult mouse liver. Mol Cell Biol. 1997 Oct;17(10):6014-22
• All: 4 reference(s)