Gpi1^a-m1H
Chemically induced Allele Detail

Summary

• Symbol: Gpi1^a-m1H
• Name: glucose-6-phosphate isomerase 1; mutant 1, Harwell
• MGI ID: MGI:2177275
• Synonyms: Gpi1^am1H
• Gene: Gpi1 Location: Chr7:33900755-33929761 bp, - strand Genetic Position: Chr7, 19.46 cM
• Alliance: Gpi1^a-m1H page

Mutation origin

• Strain of Origin: 101/H

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A T-to-C transition mutation is predicted to result in a serine to proline mutation in amino acid 277. (J:30438)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpi1 Mutation: 71 strains or lines available

Notes

Gpi1^a-m1H. This mutation was induced in strain 101/H at Harwell by treatment with ethylnitrosourea (ENU). The sequence alterations in this mutation have been determined (J:30438). Null mutant embryos have essentially disappeared by embryonic day of 9.5 (J:16100); some extra-embryonic tissue may remain as late as day 10.5, but is gone a day later (J:36586).

References

• Original: J:75638 Peters J, et al., Analysis of mutations of glucose phosphate isomerase-1, Gpi-1, in the mouse. Prog Clin Biol Res. 1990;340C:125-32
• All: 9 reference(s)