Chd7^Mt
Chemically induced Allele Detail

Summary

• Symbol: Chd7^Mt
• Name: chromodomain helicase DNA binding protein 7; metis
• MGI ID: MGI:2177297
• Synonyms: GENA171
• Gene: Chd7 Location: Chr4:8690406-8867659 bp, + strand Genetic Position: Chr4, 3.68 cM
• Alliance: Chd7^Mt page

Mutation origin

• Strain of Origin: BALB/cAnNCrl

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: A mutation in the splice acceptor site resulted in a V1688X substitution. This mutation putatively results in a protein lacking only the most C-terminal NLS, SANT, and BRK domains. (J:104123)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Chd7 Mutation: 138 strains or lines available

References

• Original: J:75619 Kiernan AE, et al., ENU mutagenesis reveals a highly mutable locus on mouse Chromosome 4 that affects ear morphogenesis. Mamm Genome. 2002 Mar;13(3):142-8
• All: 2 reference(s)