Tg(Krt1-5-cre/ERT)1Ipc
Transgene Detail

Summary

• Symbol: Tg(Krt1-5-cre/ERT)1Ipc
• Name: transgene insertion 1, I Pierre Chambon
• MGI ID: MGI:2177427
• Synonyms: K5-Cre, K5-Cre-ER^T, K5Cre^ERT
• Transgene: Tg(Krt1-5-cre/ERT)1Ipc Location: unknown
• Alliance: Tg(Krt1-5-cre/ERT)1Ipc page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Krt1-5-cre/ERT)1Ipc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Krt5

• Mutation details: This transgene expresses a tamoxifen-inducible form of cre recombinase under the control of the Krt5 promoter in epidermal tissues. (J:69324)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Krt5 (species not specified) Summary of all recombinase alleles driven by Krt5. Comparative matrix view of recombinase activities

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Tg(Krt1-5-cre/ERT)1Ipc

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:69324 Indra AK, et al., Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res. 1999 Nov 15;27(22):4324-7
• All: 32 reference(s)