Ski^tm1Cco
Targeted Allele Detail

Summary

• Symbol: Ski^tm1Cco
• Name: ski sarcoma viral oncogene homolog (avian); targeted mutation 1, Clemencia Colmenares
• MGI ID: MGI:2177555
• Synonyms: ski-
• Gene: Ski Location: Chr4:155238532-155307049 bp, - strand Genetic Position: Chr4, 86.17 cM
• Alliance: Ski^tm1Cco page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:42573
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Insertion of a neomycin resistance cassette into the exon 1 generated a small deletion in the coding sequence. (J:42573)

Expression

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	25 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Ski Mutation: 66 strains or lines available

References

• Original: J:42573 Berk M, et al., Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development. Genes Dev. 1997 Aug 15;11(16):2029-39
• All: 12 reference(s)