Tg(Camk2a-cre)1Lfr
Transgene Detail

Summary

• Symbol: Tg(Camk2a-cre)1Lfr
• Name: transgene insertion 1, Louis F Reichardt
• MGI ID: MGI:2177631
• Synonyms: CaMKcre, CamKIIcre, CaMKII-cre
• Transgene: Tg(Camk2a-cre)1Lfr Location: unknown
• Alliance: Tg(Camk2a-cre)1Lfr page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Camk2a-cre)1Lfr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Camk2a

• Mutation details: This transgene directs the expression of Cre recombinase under the control of the alpha subunit of the calcium/calmodulin-dependent protein kinase II promoter, active in the neocortex, CA1 region of the hippocampus, the striatum, amygdala, and the substantia nigra. (J:69123)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Camk2a (species not specified) Summary of all recombinase alleles driven by Camk2a. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:69123 Xu B, et al., The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB. J Neurosci. 2000 Sep 15;20(18):6888-97
• All: 14 reference(s)