Gata6^tm1Gsv
Targeted Allele Detail

Summary

• Symbol: Gata6^tm1Gsv
• Name: GATA binding protein 6; targeted mutation 1, Frank Grosveld
• MGI ID: MGI:2177784
• Gene: Gata6 Location: Chr18:11052510-11085636 bp, + strand Genetic Position: Chr18, 5.63 cM
• Alliance: Gata6^tm1Gsv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:52029
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ gene was inserted in-frame 79 nucleotides downstream of the initiation codon, followed by a neomycin resistance cassette. A beta-galactosidase fusion protein was expressed from this allele under the control of the endogenous promoter. (J:52029)

Expression

In Mice Carrying this Mutation:

55 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata6 Mutation: 35 strains or lines available

References

• Original: J:52029 Koutsourakis M, et al., The transcription factor GATA6 is essential for early extraembryonic development. (Errata: v. 126(9):U4). Development. 1999 Feb;126(4):723-32
• All: 5 reference(s)