Lmo2^tm1Thr
Targeted Allele Detail

Summary

• Symbol: Lmo2^tm1Thr
• Name: LIM domain only 2; targeted mutation 1, Terence H Rabbitts
• MGI ID: MGI:2177821
• Synonyms: rbtn2 -
• Gene: Lmo2 Location: Chr2:103788331-103812223 bp, + strand Genetic Position: Chr2, 54.46 cM
• Alliance: Lmo2^tm1Thr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:19175
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin selection cassette was inserted into exon 2. Northern blot analysis on embryonic RNA derived from homozygous mice confirmed that no transcript was produced from this allele. (J:19175)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lmo2 Mutation: 31 strains or lines available

References

• Original: J:19175 Warren AJ, et al., The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development. Cell. 1994 Jul 15;78(1):45-57
• All: 1 reference(s)