Fzd5^tm1Mmt
Targeted Allele Detail

Summary

• Symbol: Fzd5^tm1Mmt
• Name: frizzled class receptor 5; targeted mutation 1, Maketo M Taketo
• MGI ID: MGI:2177951
• Gene: Fzd5 Location: Chr1:64769717-64776907 bp, - strand Genetic Position: Chr1, 32.74 cM
• Alliance: Fzd5^tm1Mmt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:52605
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance gene was inserted into the only coding exon of the gene. RT-PCR analysis of RNA derived from homozygous embryos demonstrated that no detectable transcript was produced from this allele. (J:52605)

Expression

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fzd5 Mutation: 33 strains or lines available

References

• Original: J:52605 Ishikawa T, et al., Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development. 2001 Jan;128(1):25-33
• All: 3 reference(s)