Meg3^{Gt(pGTi)216Gos}
Gene trapped Allele Detail

Summary

• Symbol: Meg3^{Gt(pGTi)216Gos}
• Name: maternally expressed 3; gene trap 216, Achim Gossler
• MGI ID: MGI:2177961
• Synonyms: Gtl2^lacZ, Gtl2lacZ
• Gene: Meg3 Location: Chr12:109506879-109538163 bp, + strand Genetic Position: Chr12, 60.25 cM
• Alliance: Meg3^{Gt(pGTi)216Gos} page

Mutation origin

• Mutant Cell Line: gt216
• Germline Transmission: Earliest citation of germline transmission: J:30839
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: p6LSN Vector Type: enhancer trap
• Mutation details: Insertion of two to three copies of the vector pGTi into the gene. A beta-galactosidase fusion protein is expressed from this allele. (J:47969)
• Inheritance: Dominant

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Meg3 Mutation: 4 strains or lines available

References

• Original: J:30839 Schuster-Gossler K, et al., Gtl2lacZ, an insertional mutation on mouse chromosome 12 with parental origin-dependent phenotype. Mamm Genome. 1996 Jan;7(1):20-4
• All: 7 reference(s)