Tg(Pgk1-cre)1Lni
Transgene Detail

Summary

• Symbol: Tg(Pgk1-cre)1Lni
• Name: transgene insertion 1, Peter Lonai
• MGI ID: MGI:2178050
• Synonyms: Cre^mat, PGK-Cre, PGK:Cre, PGKCre, PGK-Cre^m
• Transgene: Tg(Pgk1-cre)1Lni Location: unknown Genetic Position: Chr4, Syntenic
• Alliance: Tg(Pgk1-cre)1Lni page

Transgene origin

• Strain of Origin: (BALB/c x C57BL/6)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pgk1-cre)1Lni expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Pgk1

• Mutation details: This transgene directs the expression of Cre recombinase under the control of a phosphoglycerate kinase promoter, with integration site effects. Expression of this transgene is under dominant maternal control, probably due to cis acting effects at the integration site. SNP typing indicates that it is likely the transgene integrated into a Chr 4 locus of BALB/c origin. Activity is thought to commence at the diploid phase of oogenesis, and directs complete recombination in all tissues of progeny derived from mothers carrying the transgene. (J:69332)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pgk1 (species not specified) Summary of all recombinase alleles driven by Pgk1. Comparative matrix view of recombinase activities

Disease models

Expression

In Mice Carrying this Mutation:

21 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:69332 Lallemand Y, et al., Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase. Transgenic Res. 1998 Mar;7(2):105-12
• All: 247 reference(s)