Minute
Radiation induced Allele Detail

Summary

• Symbol: Minute
• Name: minute imprinted gene in the Igf2 region
• MGI ID: MGI:2178160
• Synonyms: Minute^mat, Minute^pat
• Gene: Minute Location: unknown Genetic Position: Chr7, Syntenic
• Alliance: Minute page

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Inversion
• Minute involves 143 genes/genome features (Inpp5a, Nkx6-2, Cfap46 ...) View all
• Mutation details: The mutation in the minute mouse was shown to be an inversion, whose breakpoint distal to H19 disrupts an enhancer for Igf2 expression in skeletal muscle and tongue, and separates the gene from other mesodermal and extra-embryonic enhancers. The phenotype of the minute mouse is varying depending on maternal or paternal inheritence. (J:75952)

Expression

In Mice Carrying this Mutation:	77 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Minute Mutation: 1 strain or line available

References

• Original: J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
• All: 3 reference(s)