Fgf18^tm1Dor
Targeted Allele Detail

Summary

• Symbol: Fgf18^tm1Dor
• Name: fibroblast growth factor 18; targeted mutation 1, David M Ornitz
• MGI ID: MGI:2178751
• Synonyms: Fgf18-
• Gene: Fgf18 Location: Chr11:33067430-33097400 bp, - strand Genetic Position: Chr11, 19.21 cM
• Alliance: Fgf18^tm1Dor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75879
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1, which codes for the translation initiation site and the signal peptide, was deleted and replaced by a 7kb fragment containing lacZ and a neo cassette. (J:75879)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf18 Mutation: 10 strains or lines available

References

• Original: J:75879 Liu Z, et al., Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev. 2002 Apr 1;16(7):859-69
• All: 10 reference(s)