Cer1^tm1Bhr
Targeted Allele Detail

Summary

• Symbol: Cer1^tm1Bhr
• Name: cerberus 1, DAN family BMP antagonist; targeted mutation 1, Richard R Behringer
• MGI ID: MGI:2178818
• Synonyms: Cerl-, Cerr1-
• Gene: Cer1 Location: Chr4:82799988-82803385 bp, - strand Genetic Position: Chr4, 39.4 cM
• Alliance: Cer1^tm1Bhr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:62080
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A PGKneobpA-lox cassette replaced the entire gene coding region via homologous recombination. Southern blot analysis using a 5' cDNA fragment as a probe confirmed the deletion of the coding region in homozygous mutant embryos. (J:62080)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cer1 Mutation: 11 strains or lines available

References

• Original: J:62080 Shawlot W, et al., The cerberus-related gene, Cerr1, is not essential for mouse head formation [letter]. Genesis. 2000 Apr;26(4):253-8
• All: 2 reference(s)