Foxf1^tm1Rhc
Targeted Allele Detail

Summary

• Symbol: Foxf1^tm1Rhc
• Name: forkhead box F1; targeted mutation 1, Robert H Costa
• MGI ID: MGI:2179135
• Synonyms: Foxf1-
• Gene: Foxf1 Location: Chr8:121811125-121814883 bp, + strand Genetic Position: Chr8, 70.31 cM, cytoband E1
• Alliance: Foxf1^tm1Rhc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:70364
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The genomic sequences encoding the N-terminal winged-helix DNA binding domain are replaced with a cassette containing a LacZ gene with a nuclear localization sequence and a PGK/neo gene. (J:70364)

Expression

In Mice Carrying this Mutation:	148 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxf1 Mutation: 13 strains or lines available

References

• Original: J:70364 Kalinichenko VV, et al., Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the Forkhead Box f1 transcription factor. Dev Biol. 2001 Jul 15;235(2):489-506
• All: 11 reference(s)