Styx^tm1.1Jedi
Targeted Allele Detail

Summary

• Symbol: Styx^tm1.1Jedi
• Name: serine/threonine/tyrosine interaction protein; targeted mutation 1.1, Jack E Dixon
• MGI ID: MGI:2179184
• Synonyms: Styx^loxC/loxC
• Gene: Styx Location: Chr14:45588534-45614608 bp, + strand Genetic Position: Chr14, 22.9 cM
• Alliance: Styx^tm1.1Jedi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:74767
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A derivative of Styx^tm1Jedi, the in-frame lacZ sequence and the sequence encoding the active site of exon 7 were deleted through cre-mediated recombination in ES cells. (J:74767)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Styx Mutation: 14 strains or lines available

References

• Original: J:74767 Wishart MJ, et al., The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2112-7
• All: 1 reference(s)