Foxh1^tm1Jlw
Targeted Allele Detail

Summary

• Symbol: Foxh1^tm1Jlw
• Name: forkhead box H1; targeted mutation 1, Jeffrey L Wrana
• MGI ID: MGI:2179442
• Synonyms: FoxH1-
• Gene: Foxh1 Location: Chr15:76552425-76554148 bp, - strand Genetic Position: Chr15, 36.24 cM
• Alliance: Foxh1^tm1Jlw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:69594
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The gene was disrupted by insertion of a PGK-neo cassette via homologous recombination. Homozygous mutant embryos could be detected by PCR analysis up to E10.5. (J:69594)

Expression

In Mice Carrying this Mutation:	59 assay results
In Structures Affected by this Mutation:	12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Foxh1 Mutation: 34 strains or lines available

References

• Original: J:69594 Hoodless PA, et al., FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse. Genes Dev. 2001 May 15;15(10):1257-71
• All: 8 reference(s)