Mycn^tm1Knd
Targeted Allele Detail

Summary

• Symbol: Mycn^tm1Knd
• Name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived; targeted mutation 1, Hisato Kondoh
• MGI ID: MGI:2179462
• Synonyms: N-myc -
• Gene: Mycn Location: Chr12:12986094-12991837 bp, - strand Genetic Position: Chr12, 6.14 cM, cytoband A3-B
• Alliance: Mycn^tm1Knd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:76279
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A promoterless neomycin resistance gene was inserted in-frame into exon 2. (J:76279)

Expression

In Mice Carrying this Mutation:	16 assay results
In Structures Affected by this Mutation:	14 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mycn Mutation: 25 strains or lines available

References

• Original: J:76279 Sawai S, et al., Embryonic lethality resulting from disruption of both N-myc alleles in mouse zygotes. New Biol. 1991 Sep;3(9):861-9
• All: 3 reference(s)