Omp^tm1Mom
Targeted Allele Detail

Summary

• Symbol: Omp^tm1Mom
• Name: olfactory marker protein; targeted mutation 1, Peter Mombaerts
• MGI ID: MGI:2179520
• Synonyms: Omp-lacZ, OMP-taulacZ, (OMP)-TLZ^-
• Gene: Omp Location: Chr7:97792566-97794654 bp, - strand Genetic Position: Chr7, 53.59 cM
• Alliance: Omp^tm1Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:36595
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A tau-lacZ-loxP-tk-neo-loxP expression cassette replaced the coding exon and placed the tau-lacZ sequences under control of the endogenous regulatory sequences. Transient expression of Cre recombinase in C57BL/6 blastocysts excised the thymidine kinase and neomycin sequences. Expression of the tau-lacZ fusion protein in heterozygous mutant mice was detected in olfactory axon termini in individual glomeruli. (J:36595)

Expression

In Mice Carrying this Mutation:

11 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Omp Mutation: 27 strains or lines available

References

• Original: J:36595 Mombaerts P, et al., Visualizing an olfactory sensory map. Cell. 1996 Nov 15;87(4):675-86
• All: 11 reference(s)