Prph^tm1Jpj
Targeted Allele Detail

Summary

• Symbol: Prph^tm1Jpj
• Name: peripherin; targeted mutation 1, Jean-Pierre Julien
• MGI ID: MGI:2180052
• Gene: Prph Location: Chr15:98953055-98956859 bp, + strand Genetic Position: Chr15, 55.72 cM, cytoband E-F
• Alliance: Prph^tm1Jpj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:76218
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Exon 1 of this gene was disrupted by insertion of an nls-lacZ-neo cassette via homologous recombination. Northern and Western blot analyses confirmed the absence of gene expression in homozygous mutant animals. (J:76218)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prph Mutation: 21 strains or lines available

References

• Original: J:76218 Lariviere RC, et al., Reduced number of unmyelinated sensory axons in peripherin null mice. J Neurochem. 2002 May;81(3):525-32
• All: 5 reference(s)