Foxd1^tm1Lai
Targeted Allele Detail

Summary

• Symbol: Foxd1^tm1Lai
• Name: forkhead box D1; targeted mutation 1, Eseng Lai
• MGI ID: MGI:2180362
• Synonyms: BF-2(-), Foxd1^lacZ
• Gene: Foxd1 Location: Chr13:98490753-98493213 bp, + strand Genetic Position: Chr13, 51.96 cM
• Alliance: Foxd1^tm1Lai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:33767
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Most of the gene coding region was replaced with a PGK-neo-lacZ cassette with the lacZ gene situated downstream of the transcription initiation site. (J:33767)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxd1 Mutation: 13 strains or lines available

References

• Original: J:33767 Hatini V, et al., Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2. Genes Dev. 1996 Jun 15;10(12):1467-78
• All: 13 reference(s)