Dlx5^tm1.1Levi
Targeted Allele Detail

Summary

• Symbol: Dlx5^tm1.1Levi
• Name: distal-less homeobox 5; targeted mutation 1.1, Giovanni Levi
• MGI ID: MGI:2180475
• Synonyms: Dlx5-, Dlx5/LacZ, Dlx5-LacZ^Cre, Dlx5^tm1.1Aism
• Gene: Dlx5 Location: Chr6:6877801-6882068 bp, - strand Genetic Position: Chr6, 2.83 cM
• Alliance: Dlx5^tm1.1Levi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:56557
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was generated by breeding mice heterozygous for Dlx5^tm1Levi with CMV-Cre transgenic mice. The floxed neomycin resistance gene, which was used to delete a portions of exon 1 and 3 and all of exon 2, was excised, leaving the lacZ gene intact. (J:56557)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dlx5 Mutation: 25 strains or lines available

References

• Original: J:56557 Acampora D, et al., Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. Development. 1999 Sep;126(17):3795-809
• All: 8 reference(s)