Cd1d1^tm1Crw
Targeted Allele Detail

Summary

• Symbol: Cd1d1^tm1Crw
• Name: CD1d1 antigen; targeted mutation 1, Chyung-Ru Wang
• MGI ID: MGI:2180713
• Synonyms: M1
• Gene: Cd1d1 Location: Chr3:86903141-86906748 bp, - strand Genetic Position: Chr3, 37.91 cM
• Alliance: Cd1d1^tm1Crw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:76976
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 1.6-kb fragment containing exons 1 through 3 was replaced with a neomycin selection cassette. Transcript was undetected in homozygous mutant mice by RT-PCR analysis. (J:76976)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd1d1 Mutation: 35 strains or lines available

References

• Original: J:76976 Chen YH, et al., Expression of CD1d2 on thymocytes is not sufficient for the development of NK T cells in CD1d1-deficient mice. J Immunol. 1999 Apr 15;162(8):4560-6
• All: 7 reference(s)