Barhl1^tm1Xia
Targeted Allele Detail

Summary

• Symbol: Barhl1^tm1Xia
• Name: BarH like homeobox 1; targeted mutation 1, Mengqing Xiang
• MGI ID: MGI:2181383
• Synonyms: Barhl1-
• Gene: Barhl1 Location: Chr2:28797691-28806680 bp, - strand Genetic Position: Chr2, 19.38 cM
• Alliance: Barhl1^tm1Xia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77122
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region of the gene was replaced with a lacZ/PGK-neo casette. The PGK-neo portion of the cassette is flanked by loxP sites. (J:77122)

Expression

In Mice Carrying this Mutation:

70 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Barhl1 Mutation: 23 strains or lines available

References

• Original: J:77122 Li S, et al., Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene. Development. 2002 Jul;129(14):3523-32
• All: 4 reference(s)