Usf2^tm1Svl
Targeted Allele Detail

Summary

• Symbol: Usf2^tm1Svl
• Name: upstream transcription factor 2; targeted mutation 1, Sophie Vaulont
• MGI ID: MGI:2181387
• Synonyms: USF2-
• Gene: Usf2 Location: Chr7:30645421-30656288 bp, - strand Genetic Position: Chr7, 19.27 cM, cytoband A2-B1
• Alliance: Usf2^tm1Svl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:42599
• Parent Cell Line: CCB (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The gene was disrupted by insertion of a lacZ-neo cassette into exon 7 encoding the DNA-binding domain via homologous recombination. Western blot analysis of liver nuclear protein from homozygous mutant animals verified the absence of gene expression. (J:42599, J:75776)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usf2 Mutation: 12 strains or lines available

References

• Original: J:42599 Vallet VS, et al., Glucose-dependent liver gene expression in upstream stimulatory factor 2 -/- mice. J Biol Chem. 1997 Aug 29;272(35):21944-9
• All: 6 reference(s)