Tg(Drd1a-cre)1Gsc
Transgene Detail

Summary

• Symbol: Tg(Drd1a-cre)1Gsc
• Name: transgene insertion 1, Gunther Schutz
• MGI ID: MGI:2181424
• Synonyms: D1cre
• Transgene: Tg(Drd1a-cre)1Gsc Location: unknown
• Alliance: Tg(Drd1a-cre)1Gsc page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Drd1a-cre)1Gsc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Drd1 (MGI:99578)

• Mutation details: This transgene expresses Cre recombinase under the control of a mouse dopamine receptor D1A gene promoter. This promoter is active in the striatum, nucleus accumbens and olfactory tubercles; weak expression is also noted in layer VI of the cortex, CA2 of the hippocampus and some nuclei of the thalamus. (J:76211)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Drd1 (mouse) Summary of all recombinase alleles driven by Drd1. Comparative matrix view of recombinase activities Alliance mouse Drd1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:76211 Mantamadiotis T, et al., Disruption of CREB function in brain leads to neurodegeneration. Nat Genet. 2002 May;31(1):47-54
• All: 2 reference(s)